UK Health Radio Medical News
Update
BMJ given backing in Statin debate
In the long running debate about statins, the BBC
reports that investigation has given backing to the British Medical Journal's
handling of two controversial and inaccurate articles it published on the harms
of cholesterol-reducing statins. Both of
which claimed that 20% of users would suffer harmful side effects. Statins are
given to lower levels of cholesterol in the blood to reduce the odds of a heart
attack or stroke.
The journal withdrew the claim, but refused a full
retraction.
Prominent academics, however, continue to demand a
retraction criticising the investigation and saying that the articles still
damage confidence in statins.
The pros and cons of the drugs became a hugely contentious
area of medicine in the run-up to a massive prescribing expansion in July. Four
in 10 adults in England, Wales and Northern Ireland are, according to
guidelines, now eligible for statins, even although many of that number are at
low risk of a heart attack or stroke.
Claims had been made by Dr John Abramson, from
Harvard Medical School and, writing separately, by cardiologist Dr Aseem
Malhotra that claimed that the side effects of statins affected 18-20% of
people taking them.
However the research they quoted did not adjust its
findings for the level of those side effects - such as liver inflammation,
increased risk of diabetes and muscle problems, which would have arisen even if
people were not taking the drugs.
Leading academic Prof Rory Collins, from Oxford
University, said that the articles could have encouraged people to stop taking
statins with potentially life threatening consequences.
The 20% figure for side effects was eventually
withdrawn, but the reports have not been retracted.
Amanda Thomas
UK Health Radio Medical News
Update
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